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Undergraduate Research Showcase

Undergraduate research is the exploration of a specific topic within a field by an undergraduate student that makes an original contribution to the discipline.

Understanding Low-Dense Lipoprotein and Macrophages in Cardiovascular Disease


Chelsea LennoxMy name is Chelsea Lennox, I am a sophomore studying Computer Science and a member of the VECTOR Research Program. With a passion for computer science, public health, and research, I aspire to dive deep into technology and the research world. Part of being a computer science student includes continuous learning. A great way for me to apply my programming skills and public health knowledge was through research.


ABSTRACT:  Cardiovascular disease has made its progression to cause the mortality rate to rise. This disease can be obtained inheritably or by an inadequate lifestyle. The contributing factors that cause cardiovascular disease to develop are low-density lipoprotein and macrophages. A coronary artery model was programmed to show a visualization of the development of the cardiovascular disease. In the heart anatomy, there are two main arteries; left and right coronary arteries. When the artery reaches abnormalities such as an increase of low-density lipoprotein leads to a blockage and low blood flow called Artherosclerosis.  Atherosclerosis is the main cause of cardiovascular disease. The accumulation of low-density lipoprotein occurs in the innermost layer of the coronary artery which can develop as early as childhood through adulthood and continue to accumulate causing cardiovascular disease. Thus, the presence of an abundance of low-dense lipoprotein results in a plaque-buildup which can rupture and causes the tissues to depart and lead to a heart attack.


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Faculty Mentor

Osama Moussa

Professor of Physics

East Campus

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